NMN stands for Nicotinamide Mononucleotide. This is a small molecule that naturally occurs in all living forms. NMN is a bioactive nucleotide which is one of the age-controlling molecules playing an active role in boosting NAD+ levels (central molecule supporting human existence).
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NAD+ is a very important and small molecule, without which we would die in seconds. The biggest issue with NAD+ is its shrinking levels while we age.
Luckily, it is possible to enhance NAD+ levels by supplementing it with NAD precursors. Out of the precursors known so far, NMN is considered to be the most effective to maintain or increase NAD+ levels.
Also, they help to activate the Sirtuin genes, important to accelerate DNA repair and cell survival and development.
With age, our bodies start getting frail and produce less energy, become vulnerable to inflammations and infections, and experience cognitive degeneration and aging-related memory decline.
Also, one of the commonly possible outcomes of unhealthy aging is obesity. The latter is one of the causes of the vast amount of NAD+ depletion.
To prevent this from happening, you can choose to augment your NAD+ levels with NMN supplementation. The benefits of high NMN supplies and hence increased NAD+ levels in the body include
– Glucose tolerance
– Improved Insulin sensitivity and signaling
– Improved blood circulation
– Age-induced excess body weight suppression
– Muscle endurance
– Restoration of better cognitive function
– Enhanced energy metabolism
– Improved mitochondrial function
– DNA protection
– Prevention of age-related gene mutation
A famous study conducted by Dr. David Sinclair and his colleagues in his Lab at Harvard Medical School documented heightened energy levels among older mice. The study was conducted with 12-month-old mice who were fed nicotinamide mononucleotide (NMN) blended in their drinking water.
Dr. Sinclair mentions “The effects of NMN are similar to that of dieting and exercise. The mice are leaner and have more energy. Plus, they run further on the treadmill”.
Also, many people using NMN supplements show remarkably high energy levels and the ability to concentrate.
During the first stages of NMN studies, this molecule was considered crucial for producing cellular energy and NAD+ augmentation.
Further, many anti-aging benefits of NMN were also observed. These benefits were later connected with the prevention of neurodegenerative diseases, and cognitive decline (including Alzheimer’s and Parkinson’s diseases). Plus, numerous therapeutic effects on type 2 diabetes, obesity, cardiac and cerebral ischemia, and heart failure.